What is Liver Fibrosis
Liver fibrosis is a pathological condition characterized by the accumulation of excessive scar tissue (fibrosis) in the liver. This process occurs as a response to chronic liver injury, inflammation, or other damaging stimuli over an extended period.
Symptoms of Liver Fibrosis
Liver fibrosis itself often does not cause noticeable symptoms in its early stages. As the condition progresses, symptoms may develop depending on the underlying cause and the extent of liver damage.
Causes of Liver Fibrosis
Chronic Viral Hepatitis
Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are major causes.
Autoimmune Hepatitis
Chronic autoimmune inflammation can damage liver cells and trigger fibrosis.
Excessive Alcohol Consumption
Prolonged heavy drinking can lead to alcoholic liver disease and fibrosis.
Medications
Certain toxins, drugs, and medications can cause liver damage and fibrosis.
Non-Alcoholic Fatty Liver Disease (NAFLD)
Obesity, insulin resistance, and metabolic syndrome can lead to fat accumulation in the liver, which may progress to fibrosis.
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Diagnosis of Liver Fibrosis
Blood Tests
Liver function tests (e.g., ALT, AST) and markers of liver fibrosis (e.g., FibroTest, APRI score).
Imaging Test
Ultrasound, CT scan, or MRI to assess liver texture and detect signs of fibrosis
Liver Biopsy
Gold standard for definitive diagnosis, providing detailed information on the degree of fibrosis and presence of inflammation.
Liver Fibrosis Treatment in Ahmedabad
Addressing Underlying Causes
Treatment of viral hepatitis, cessation of alcohol consumption, management of metabolic conditions.
Lifestyle changes
Healthy diet, weight management, avoiding alcohol and toxins.
Medications
antiviral medications or medications to reduce inflammation and fibrosis may be prescribed.
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Dr. Ankit Patel
Dr. Ankit R. Patel, Consultant Medical Gastroenterology, Hepatology and Endoscopy at Kaizen Institute of Gastroenterology & research centre, has completed his graduation & post graduation from Pramukhswami Medical College, Karamsad, Gujarat and completed DNB Gastroenterology and Hepatology training at Apollo Hospital, Chennai. He was awarded degree of Diplomate of National Board (DNB – Medical Gastroenterology) by NBE.
Best And Experienced Gastroenterologist In Ahmedabad
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Prevention of Liver Fibrosis
- If you drink alcohol, do so in moderation. For most adults, this means up to one drink per day for women and up to two drinks per day for men.
- Obesity and metabolic syndrome are major risk factors for non-alcoholic fatty liver disease (NAFLD) and subsequent fibrosis.
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Read All The Frequently Asked Questions About Liver Fibrosis
FAQ’S
Yes, early-stage liver fibrosis can be reversible with appropriate treatment and lifestyle changes. Managing underlying causes such as viral hepatitis, alcohol cessation, weight loss (in NAFLD), and treating underlying conditions can halt or reverse fibrosis.
Liver fibrosis is the early stage of liver scarring, where there is excess deposition of scar tissue in response to injury. Cirrhosis is a late-stage liver disease characterized by widespread fibrosis, nodules, and loss of liver function. Cirrhosis is irreversible, while fibrosis may still be reversible if caught early.
Untreated liver fibrosis can progress to cirrhosis, which increases the risk of liver failure, portal hypertension, liver cancer (hepatocellular carcinoma), and other serious complications.